Announcements
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A call for ecology papers
Open for submissions -
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Targeted illumination confocal microscopy enables in vivo voltage imaging in thick tissue
A fundamental mechanism for information processing in the brain is electrical activity. However, observing such activity at the single-cell level is challenging. We have developed an optical microscope that combines the advantages of targeted illumination and confocal gating to enable kilohertz-rate voltage imaging across large fields of view in thick tissue.
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Method of the Year 2023: Methods for modeling development
Methods for modeling development is our Method of the Year 2023, for the remarkable insights that recent methodological advances have enabled in our understanding of the molecular mechanisms of human embryogenesis.
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Method of the Year: spatially resolved transcriptomics
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Accurate and efficient integrative reference-informed spatial domain detection for spatial transcriptomics
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Systematic assessment of long-read RNA-seq methods for transcript identification and quantification
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Large-scale foundation model on single-cell transcriptomics